Allevi Author: Plant Based Hydrogels for Cell Laden Bioprinting

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Time for another inductee to the #AlleviAuthor club. Researchers from University of California, Berkeley and IBM used their Allevi 2 bioprinter to study the printability and viability of plant based bioinks.

In their paper titled, “Agarose-Based Hydrogels as Suitable Bioprinting Materials for Tissue Engineering” and published in ACS Biomaterials Science & Engineering, they compared agarose-based hydrogels commonly used for cartilage tissue engineering to Pluronic. The goal is to find a bioink that has great printability without sacrificing cell viability.

The team compared mechanical and rheological properties, including yield stress, storage modulus, and shear thinning, as well as construct shape fidelity to assess their potential as a bioink for cell-based tissue engineering. Read on to find out which ratios of alginate and agarose demonstrated the best cell viability as well as print structure for their cartilage tissue engineering needs:

10 Cools Things You Could Print with a 3D Bioprinter in the Near Future

3D bioprinting is an intuitive way to approach biology. But not many people realize its versatility. To give an idea of what is possible through 3D bioprinting, we’re starting a little series called “Allevi Applications.” Hopefully, this will make the idea of bioprinting a little more accessible! So without further ado, let’s get started.

1. Joint replacements, think knee, ankle and elbow.

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2. Microfluidic chips

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3. Cell scaffolds for replacement organs, eventually making fulling functioning organs

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4. Cartilage

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5. Accurate surgical models for physicians to practice difficult procedures

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6. Drugs with custom release rates, compositions and geometries

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7. Teeth and dental implants

8. Skin grafts for burn victims

9. Casts and bioactive clothing

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10.  Blood vessels, arteries and heart valves

And our users are just getting started. Check back as we cover new publications from #Allevi Authors and see what amazing applications they come up with next.