In the USA alone, 500,000 bone grafting procedures are performed annually, with musculoskeletal-related disabilities costing about $240 billion each year. In spite of the advancements over the past 20 years, scientists and engineers have been unable to provide a material that fulfills every characteristic needed for bone tissue to be physiologically relevant in clinical applications.
In this edition of the #AlleviAuthor series, our very own Director of Bioengineering, Taci Pereira, reviews state of the art bone tissue biofabrication technologies for the Journal of 3D Printing in Medicine.
Pereira examines the six essential characteristics of bone graft materials; osteoinduction, osteoconduction, osteointegration, biocompatibility, translatability, and growth factor necessity.
In addition to reviewing bioinks for bone engineering, Pereira examines the different techniques that have emerged within the biofabrication field; 3D bioprinting, selective laser sintering (SLS), electrospinning and stereolithography.
Read on below to learn about the promising methods for bone engineering, where Pereira sees a need for innovation and why she is excited for the future of Hyperelastic Bone.